May 5, 2025
Science

A historic principle was signed in pig-to-human kidney transplantation

  • August 17, 2023
  • 0

Our organs, which are naturally worn out, are accompanied by diseases and advanced levels. dead can bring. But even donations made today cannot meet the demand for organ

Our organs, which are naturally worn out, are accompanied by diseases and advanced levels. dead can bring. But even donations made today cannot meet the demand for organ transplants. For this reason, humanity will now be able to eliminate the need for organ transplantation, can prolong life in the future He began to look for ways.

It is the most suitable option of these ways in terms of compatibility with our body. pig organ transplantationstarted from 2021. In October 2021, for the first time in history, a pig kidney and a pig heart were transplanted into a human. big news more came.

A first was achieved in the transplantation of pig kidneys:

A team of surgeons led by Jayme Locke of the University of Alabama has announced that for the first time in history, a pig kidney transplanted into a human in a genetically modified form has succeeded in exerting “vital kidney function.” The relevant function iscreatinine clearanceIn other words, the function of the kidneys to clear out creatinine, the organic waste produced by muscle metabolism.

Such results have not yet been obtained in animal-to-human kidney transplants:

“While xenotransplantation offers a potential solution to renal deficiency, previous reports of xenotransplantation of the pig kidney to human using a preclinical model of human brain death demonstrated xenograft urine production but not creatinine clearance, a function necessary to to survive. Therefore, to date, no studies have shown that a xenograft can provide life-sustaining renal function in a human.”

A successful transplant has not been done in a living individual. Genetically modified pig kidney, 52 years old by accident brain dead and handed over to an unnamed male person who voluntarily donated his body.

The kidney continued to perform all functions until the termination of life support, which was provided to the individual’s body and continued to keep its organs alive. This process It was exactly 7 days.

With this success, the team performing the transplant has not left a kidney with a person whose body is donated for research, with the consent of his family and before his death. Observe for 30 days it will work.

All the details of the latest work were shared on the JAMA network.

Source: Web Tekno

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