Alzheimer’s disease every year millions of people and the treatment process of this disease is quite complex and difficult. The reason for this situation is that the causes of the disease are not fully understood. A new study could mark a major breakthrough in understanding the causes of the disease.

In the brains of Alzheimer’s patients harmful tau protein It’s piling up. Scientists studying this protein discovered an enzyme that could cause this protein to accumulate. Under normal circumstances, tau protein supports nerve cells in a healthy brain to work well It helps. In Alzheimer’s patients These proteins behave abnormally and form structures that scientists call “knots.” These junctions damage communication between nerve cells and negatively affect abilities such as memory and thinking.

Enzyme called TYK2 may be the cause of Alzheimer’s disease

In the study conducted in the US, TYK2 It was revealed that the enzyme tau makes tau proteins harmful. This enzyme adds a special tag to the tau protein, making it harder for the brain to remove harmful tau proteins. The researchers found that when they blocked this enzyme, the accumulation of tau in the brains of mice decreased and nerve cells showed signs of recovery.

This discovery also reveals new hope for the treatment of Alzheimer’s. Because some drugs that inhibit the TYK2 enzyme for the treatment of other diseases Even though it has been tested on humans. Research is being done into whether the medicines can reach the brain and what the possible side effects are.