Today it is known in the scientific world that the chemical characters associated with important parts of the genetic sequence change with environmental events. even that from generation to generation transfer is considered possible.

intergenerational epigenetics This condition, which is called heredity; indicates that the health, lifestyle and even the environment of parents can influence the health and development of other generations. Although this situation is clearly visible, it is not known how it is handled. A study published July 26 on PNAS also explored this issue and found findings about how our family parents influence our genes.

Epigenetic changes can be transmitted through sperm

Researchers conducting a study on worms found that a common epigenetic modification through semen revealed how it can be passed down over three generations, affecting gene activities and offspring development. While experts say the evidence is insufficient for humans, he added that the study reveals a lot.

Biologist Susan Strome, one of the scientists, also said in her statements: “The results show a causal relationship between histone markers transmitted by sperm, gene expression and development in offspring.” used his statements.

Epigenetics is the study of changes in gene expression without changing the actual sequences in the gene. That is, smoking, environmental pollutants, etc. While they don’t affect your DNA sequence, epigenetic changes can change the way your body reads a DNA sequence. The cell’s genome reading mechanism may not be able to access certain genes when large molecules enter their pathway, and as a result, these genes cannot be converted into proteins. Also, wrapping DNA strands around proteins called histones can achieve the same effect.

Research could help shed light on epigenetic inheritance

After fertilization, most of these epigenetic modifications is removedIn this way, cells were thought to be reprogrammed to ensure normal development. But studies in many animals, including mammals, have shown that epigenetic changes can escape and be passed down from generation to generation. Recent research on worms has also looked at whether these epigenetic features are preserved or reprogrammed in embryos, and their effects on gene expression in other generations.

Basic protein that allows DNA to be packed more densely histone Epigenetic marking has been the focus of experiments. The experts then fertilized the worm eggs with sperm with fully marked chromosomes. When the gene activity levels in the offspring were examined, it was seen that the genes in the sperm were not suppressed. This showed that the epigenetic changes were preserved and the transition to the offspring was assured.

That’s what Storme is all about.”This is if the DNA packaging pattern in the germline is preserved. can be passed on from generation to generation reveals” said. Of course, these findings are specific to worms, to humans. very few It must be repeated what you said.

While human research on this topic is quite sparse, some have found links to things like smoking habits and childhood asthma. The team thinks research on worms could help illuminate the implications of epigenetic inheritance for future generations.