While humanity has just begun to test the capabilities of gene editing technology, another historic first has been achieved in the scientific world. Scientists with two male mice without a female mouse seven mice to suit.

The birth of mice with two biological fathers, the birth of a male mouse Thanks to the conversion of XY chromosomes to XX it came true. The team, led by Katsuhiko Hayashi of Osaka University, took the next step after transforming the chromosome.

Chromosome-modified male mice produced eggs:

The skin cells of the male mouse whose chromosome had been altered were used to make immature eggs called ‘oocytes’. But this process was quite grueling.

These cells with X and Y chromosomes are reprogrammed to ‘pluripotentthey were transformed into stem cells. In other words, cells became cells that could turn into any cell type.

In the next step, the Y chromosome in these cells was completely deleted and the X chromosomes were copied. These cells were later transformed into egg cells.

The final step was the fertilization of these cells. But this stage was not so successful. According to Hayashi’s explanation, seven mice were born with these cells. Only one in 100 fertilized cells survived and was born.

What does this success mean for the future?

Speaking to the BBC, Hayashi is in the future. two partners of the same sex She shared that she wished she was capable of fertility. Moreover, with the newly developed technique, women with genetic problems on an X chromosome She also stated that she would have a chance to have a child.

Ethics, on the other hand, is a completely different framework:

While Hayashi and his team have achieved groundbreaking success, this success will only be applicable to humans in days when ethical discussions meet on a common ground. Because if similar studies are done in humans today, it will lead to major social debates.

It is currently not possible to apply the technique to humans:

The technology and technique that Hayashi and his team are using for chromosome change is not yet applicable to humans, as mice are very different from humans. But according to Hayashi, the future in 10 years The scientific world will also reach this stage.