Last Wednesday was a first in the history of medicine. US Food and Drug Administration (FDA), from human feces approved a manufactured pill for the first time. Developed by Seres Therapeutics and wow The drug can be used in people 18 years and older. The drug is expected to debut in the US in June 2023.

In fact, this isn’t the first drug produced from human feces to be approved. Used via rectum based enema in December 2022 a treatment was approved and registered for the first time. Vowst is produced in this way and to be the first oral drug passed.

The Vowst drug will be used to prevent the recurrence of an infection called “Clostridoides difficile”

Like the previously approved treatment, the Vowst pill, which contains live bacteria, Clostridioides difficile It will be used as a preventative method against recurrent bacterial infections. This product, which broke new ground with its oral intake, healthy human gut bacteria from donated feces and offers a new way to prevent infection. Clinical studies have shown that those taking the drug are more than three times less likely to re-infect.

The infection, called C.diff for short, occurs after patients take antibiotics for another infection. Antibiotics can upset the balance of bacteria that normally fill the gut and cause C.diff to multiply. When multiplying rapidly, they can cause diarrhea, abdominal pain, fever, colitis (inflammation of the colon), and in some cases can secrete toxins that can cause organ failure and even death. every year in the US 15 thousand to 30 thousand It should be noted that people have died from causes related to C.diff infections.

According to the data, those who recover from C.diff have a one in six risk of re-infecting two to eight weeks later. The risks increase with each recurrence. Here too, treatments produced from human feces, such as Vowst, are intended to come into play and prevent the infection from returning.

A major step forward against life-threatening infections, Vowst will be an adult treatment taken orally as four capsules once a day for three consecutive days. According to the FDA, the first dose of C.diff will be taken four days after the end of antibiotic treatment. In clinical trials, such as abdominal bloating, tremor, weakness, diarrhea your side effects It was added by the FDA that it was seen that it could happen.