A group of Chinese scientists has developed an imaging biomarker for Parkinson’s disease that will reliably diagnose the disease at an early stage and measure the results of clinical trials for its treatment.
reported CGTN reports Ukrinform.
The authors of the study noted that the main scientific problems in their research on neurodegenerative diseases, including Parkinson’s disease, are early detection and the search for ways to delay or even prevent their development.
As Professor Zhang Zhentao of Wuhan University, one of the members of the research team, explains, Parkinson’s disease is characterized by the accumulation of α-synuclein clusters in Lewy bodies (LB).
However, there are not enough markers for LB to diagnose Parkinson’s in the early stages, so the diagnosis of this serious disease mainly depends on the observation of clinical symptoms and detecting the disease in the late stages.
The research team developed a low molecular weight compound with high selectivity for LB, which could provide an objective basis for the early diagnosis of Parkinson’s and be of great scientific and clinical importance in slowing or preventing disease progression.
The work by Chinese scientists was published in the journal Cell, a specialized American publication that publishes scientific papers in biological disciplines such as molecular biology, biochemistry, genetics, neurobiology, virology and tumor research.
Parkinson’s disease, or rocking stroke, is a slowly progressive chronic neurological disease that is characteristic of the elderly. The disease is caused by the progressive destruction and death of neurons in the central nervous system that produce the neurotransmitter dopamine.
Modern medicine is not yet able to cure the disease or slow down its progression (etiological or pathogenetic treatment), but current conservative and operative methods of treatment allow to significantly improve the quality of life of patients.
As he reported Ukrinform, Ukraine has launched a national program to promote digital cancer diagnostic technology, which will double the speed of detecting malignant tumors.
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