A team of Japanese scientists is working with pharmaceutical company Toregem Biopharma Co. They are working on the world’s first drug that stimulates the growth of new teeth in humans.
This was reported by Kyodo News, Ukrinform reported.
In addition to primary and permanent teeth, most people also have “tooth buds” that can become new teeth. Often these “beginnings” do not develop and eventually disappear.
Scientists have developed a drug containing antibodies that block a protein that inhibits tooth growth. The drug acts on the “tooth buds” and stimulates their growth.
Toregem Biopharma Co., funded by Kyoto University, is expected to begin clinical trials in adults around July 2024.
Starting in 2025, scientists also plan to conduct a clinical trial of the drug for children aged 2 to 6 with anodontia, that is, children born without some or all permanent teeth.
Children will be given a dose to stimulate tooth growth. The drug is planned to be used in adults who have lost their teeth due to caries in the future.
Researchers plan to bring the drug to market around 2030.
The team succeeded in growing new teeth in mice in 2018. That same year, scientists introduced a drug that could grow new teeth in ferrets, mammals whose milk and permanent teeth are similar to human teeth.
As Ukrinform reported, a group of researchers from Japan found that the use of oxygen combined with the addition of hydrogen increased the survival rate of patients with cardiac arrest.
The photo is self-explanatory