April 29, 2025
Science

The genetic code of the Y chromosome that determines our sex has been fully mapped for the first time

  • August 24, 2023
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Scientists have signed a study that has the potential to pave the way for major developments in the medical world. Only men for the first time in history

The genetic code of the Y chromosome that determines our sex has been fully mapped for the first time

Scientists have signed a study that has the potential to pave the way for major developments in the medical world. Only men for the first time in history of the Y chromosome Fully mapped. So it is possible to get much more detailed information about some diseases and conditions, such as some types of cancer, human evolution, infertility and even aging. is opened.

XX and XY in a healthy individual a pair of chromosomes consists. The Y chromosome, which determines sex, has not yet been fully mapped. This is due to the chromosome too repetitive and complex There had to be a series. Thanks to the latest investigations, this great mystery has been dropped.

Y chromosome repeats all sequences to protect against mutation!

Y chromosome fully mapped

X and Y chromosomes have opposite base sequences. These bases are adenine, cytosine, thymine and guanine. Also the fact that the bases are arranged among themselves in a certain order genetic code forms. The reason why the Y chromosome has too many repeats in base sequences has been understood by recent studies. Y chromosome, possibly against mutations backup sequences created. Also some of these repetition zones production of sperm used for functions like

NHGRI team of scientists, working at the US National Institutes of Health, over 30 million During their base-pairing studies, they found that nearly half of the information encoded on the Y chromosome was exactly the same. Imagine a book full of pages. in this book half of the paragraphsIt’s written exactly the same way. This detection led to complete mapping of the Y chromosome.

It was also understood how the mapped chromosome differs between people.

Differences in DNA

Scientists who mapped the Y chromosome found in a second study that these chromosomes between different people They also looked at how they differ. Normally, two people share 99.9 percent of their DNA. of the 0.01 percent it was known to make a difference. The study examined the differences between the Y chromosome of an individual known to be of European descent and the Y chromosome of 43 individuals, half of whom are known to be of African descent.

The results were astonishing. Scientists estimate between 45.2 million and 45.2 million Y chromosomes. 84.9 million units They found that there were differences in base pairs in the range. But how this affects human health could not be understood with the available data. And why and when does the Y chromosome undergo such differentiation? unsure. As a result, during pregnancy, the X chromosomes in mother and father mixed with each other, while the Y chromosomes were inherited directly from the father. That is, the probability of changes in millions of base pairs. was low. It seems new research will help shed light on such unknowns.

Source: Web Tekno

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