have a form of skin cancer melanomaIt is one of the deadliest diseases. So much so that an average of 60,000 people die worldwide every year and hundreds of thousands of people become infected with the disease. That is why research into the treatment of skin cancer is of great importance.

The new mRNA vaccine developed by Moderna and MSD companies, which has the potential to change everything about melanoma, was one of them. An important development has now taken place in this area. mRNA-4157 called, The world’s first “personalized” mRNA vaccine against melanoma The vaccine, known as Vaccine, was tested in Britain.

It is developed specifically for each patient and prevents the disease from returning.

*The patient’s name was Steve Young, one of the first people to try the vaccine. Young had surgery in August last year for a melanoma tumor on his head.

Currently, surgical treatment is largely used for the treatment of skin cancer. Radiotherapy, medications and chemotherapy are also sometimes used treatments. The newly developed vaccine is developed specifically for each patient prevent the disease from returning goals.

Phase 2 trials showed that the vaccine significantly reduced cancer recurrence in melanoma patients. The results, published in December, showed that people with high-risk melanoma who received the vaccine had a much lower risk of dying or having their cancer come back three years later than others. Now is the final step phase 3 trials in hundreds of patients in Britain started.

What is meant by ‘personalized vaccine’?

The vaccine is a neoantigen therapy. It is designed to activate the immune system so that it fights against the patient’s specific type of cancer and tumor. So your body hunting cancer cells to prevent the disease from returning offers. It’s the same technology used in the COVID vaccine. MRNA-4157, which targets tumor neoantigens, encodes up to 34 neoantigens and activates an anti-tumor immune response based on the patient’s cancer.

Let’s also talk about personalization. Researchers will make the vaccine patient-specific A sample of the tumor during their surgery they take it. DNA sequencing and artificial intelligence are then used. The result is a vaccine produced specifically for the patient’s tumor. It is stated that it will be different for each patient, and the vaccine given to one patient will not work in another.

One of the names behind the research is Dr. Heather Shaw emphasized that their ultimate goal is to permanently cure cancer. The 3rd phase will be applied to a larger number of people than the previous phases. Goals 1. About 100 people fit. We hope it will work.

Can also be applied to other types of cancer

Shaw said there is a possibility that this vaccine could be used not only for skin cancer, but also for other cancers. According to the statement, researchers have; It also performs tests for lung, kidney and bladder cancer.