Alzheimer’s, is undoubtedly one of the most common and dangerous diseases today. Unfortunately, there is no definitive treatment yet. That is why an early diagnosis is very important. A new study conducted by researchers in Spain offers a method that could be very useful in this regard.

Researchers from the Bioengineering Institute of Catalonia in Barcelona have discovered a brand new biomarker. This discovered biomarker probably causes Alzheimer’s disease. can detect the disease before symptoms even appear was expressed. The findings were published via Biochimica et Biophysia Acta (BBA) – Molecular Basis of Disease.

A microRNA molecule accessible through body fluids occurs in high concentrations in the very early stages of Alzheimer’s disease

The biomarker in question is miR-519a-3p A molecule called microRNA. The team thinks this could be an essential early warning system for Alzheimer’s disease. According to the study, this molecule may occur in higher concentrations in Alzheimer’s patients.

Molecule, PrPC associated with cellular prion protein, also known as The level of this protein, which is known to be higher in the body in the early stages of Alzheimer’s disease decreases as you progress. Experts were able to achieve these results through brain tissue and chemical tests of deceased Alzheimer’s patients. In the early stages of the disease, high concentrations of miR-519a-3p were observed in the tissue.

miR-519a-3p, Alzheimer’s can be detected at a very early stage and palliative treatments can be applied. can offer. At the same time, scientists believe that the disease Let’s take a closer look at how it develops will also allow it. Neuroscientist Jose Antonio Rio said of his discoveries: “Currently, tests to diagnose Alzheimer’s disease are usually performed after the onset of symptoms. “This microRNA detection has the potential to help establish additional criteria in the very early stages of the disease.” He uses the expressions.

MicroRNAs, such as miR-519a-3p, are called RNA molecules that we can define as genetic materials that help cells manage protein production. They tend to be stable in the body and They can be detected in body fluids. This makes them a very useful biomarker for warning of diseases, measuring response to treatments and understanding general health status.

There is no definitive evidence yet that this molecule can be an early warning sign of Alzheimer’s disease. However, there is strong evidence that this could happen. More research will provide more definitive information on whether it can actually be used. The next step will be to validate the molecule in blood samples from different groups. If it is successful, we can use it in the clinical diagnosis of the disease.