Even if half of it is taken over time The liver that can return to its original state The surprising renovation process raises some questions.

LiverCan it be forgiven again and again because it can renew itself?

The liver is one of the most impressive organs in the human body.

Even if a significant portion of a person’s liver is donated, this organ can return to its previous size in a short time. Naturally, this feature brings to mind many ideas about organ donation. Ability to be forgiven over and over againdoesn’t it seem high to you?

But alas, donating the liver at regular intervalsit doesn’t seem as possible as we thought.

Research shows that it takes several months for the liver to regain its function and reach its previous mass.

Of course, this process the actual regenerative capacity of the organ That doesn’t mean he did. Regeneration is a phenomenon that occurs in some animals, especially salamanders. When a salamander loses a limb, the cells in the area where the loss occurred return to their previous developmental state and enter the process of differentiation to regain the functions of the lost limb.

In this situation to compensate for the loss All necessary cell types proliferate to form an exact replica of the lost limb.

In the liver, however, the situation is very different.

remaining liver cells, to compensate for the loss It multiplies by dividing, but no real differentiation occurs in this process. This means that when the removed portion grows back, it cannot exactly replicate the layout of the original tissue in terms of cell organization and arrangement of blood vessels.

This type of cell proliferation is compensatory It’s called hyperplasia and causes significant changes in the anatomical structure of the liver, while maintaining its functionality. This can cause problems in cases where the liver needs to be retransplanted, for example, because the regrowing liver tissue may have difficulty connecting to the recipient’s blood vessels and unexpected problems may occur during the functional integration process.

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