As soon as we read a sentence neurons quickly ignite electrical signals and they communicate with each other† Scientists are still unsure about how this communication proceeds. However, as a result of an investigation, it was revealed how the brain communicates with itself, and even a new treatment method can be found by changing this method of communication.

A biochemical team from Stanford and other universities has discovered what kind of communication takes place between neurons thanks to chemical species produced from synapses. The study was led by Soham Chanda, an assistant professor in the Department of Biochemistry and Molecular Biology at Colorado State University. The study, published in Nature Communications, In the lab as well as a tested live identity of synapses between neurons by enzymatic means found that it can be changed.

This method can also be used to treat brain diseases.

In lab experiments, Chanda and her colleagues made a series of changes at synapses in neurons, revealing only a few genes. With enzymes alone, changes were made in the synapse, that is, the communication, between the exciters and inhibitors. This change in the brain’s communication with itself is caused by problems in synaptic information processing and exchange. treatment of brain diseases an important one for treatment tool it could be.

Chanda said they know very little about how the human brain works and explained that they conducted this study to understand how neurons communicate with each other. Chanda, “Understanding synapse formation and its underlying functioning will also have huge implications for understanding brain diseases.” said.

The results showed that cell adhesion proteins, which mediate the brain’s communication with itself, are not the only providers that help the communication take place. So chemicals called neurotransmitters that are released from where the information comes from also seem to play an important role in controlling what type of synapse forms where and how.

One of the other teams involved in the study, the CSU team, used stem cell-derived human neurons to see their abilities in the controlled release of certain neurotransmitters and the generation of certain types of synaptic connections. The team at the University at Buffalo used a similar method in living mouse brains.