Errors in the human gene are considered a part of life. As we get older and the number of DNA increases, small problems begin to appear in our genes, such as a misplaced letter or repeating some mistakes. These errors accumulate over time and can form a mosaic of cells with unique codes in our bodies. Some cells may even lose all their chromosomes.

Scientists a lot of men loses Y chromosomes as you age He knew and looked for reasons. The extent of the loss of the Y chromosome was unknown and it was even considered a sign of aging, such as graying of the hair with age, which had no clinical significance. However, the latest research has shown that the loss of the Y chromosome is extremely important.

Y chromosome loss causes serious heart disease

Chromosomes, a set of DNA found in pairs in each cell, XX in women, in men if XY It has an X and a Y chromosome. As a result of the study, the loss of Y chromosome in the cell is called mlOY, age 70 and above in 40% of men appeared to occur. Even if the Y chromosome was long thought of as a shrinking genetic space filled with junk DNA fragments, loss of the Y chromosome can cause serious health problems.

A team of researchers announced that they had found that men over the age of 60, in particular, die faster than women and age faster biologically. With this new research why men die earlier than women Certain clues have emerged. In experiments on mice, a special gene-editing tool was used to better understand the effects of loss of the Y chromosome in the blood. CRISPRhad been used. Loss of the Y chromosome hardens heart tissues in mice injected with the specific gene and heart failure associated with heart fibrosis It was found to cause a condition known as: As a result of this situation, it was shared by the research team that early deaths were seen in mice with loss of Y chromosome.

Why Y Chromosome Loss Is So Deadly Has Been Found

The researchers also analyzed data collected from the UK Biobank study, which spanned nearly 10 years of research, to compare the findings with human data. As a result of studies and experiments, the effects of Y chromosome loss in men were thoroughly investigated. As a result, loss of Y chromosome is more die young and Alzheimer’s as well as a greater chance of suffering from age-related conditions such as: heart and vascular disease and found that it had a direct effect on heart failure.

The research team also found that men with mlOY in their blood at the start of the study had an increased risk of dying from heart failure and other cardiovascular diseases during the mean follow-up period of 11 years. In other words, as a result of this research, it is considered concrete evidence that the loss of the Y chromosome has direct harmful effects on men’s health.

There is no cure for the condition yet, but researchers say quitting smoking may be a smart move. Research also shows that men who smoke are three times more likely to lose Y-chromosomes in their blood cells than non-smokers.