Academician, molecular biologist and biochemist, one of Turkey’s leading scientists Aziz Sancarfor his work in 2015 to map how cells repair damaged DNA and preserve genetic information at the molecular level. Nobel Prize in Chemistry He was awarded the Nobel Prize and became the second Turk to receive the Nobel Prize.

Now it turns out that the 75-year-old scientist has made another discovery. According to an article written by Orhan Bursalı of Cumhuriyet, Sancar and his team have achieved a major breakthrough in the treatment of brain cancer.

The discovery was made by accident

According to the news, Sancar and his team found that the materials used in the experiments conducted in the labs EdU molecule discovered that it can be used in brain cancer. While the findings of the study were stated to have been published in the journal PNAS, it was also mentioned that Sancar spoke on the subject in the early stages. The famous scientist stated that they made their discovery by chance and that it would make many people happy: “This is a very surprising discovery, a great coincidence. While we were doing another experiment, something completely different happened that suddenly shocked us.”

The news from Bursalı also mentioned that Sancar briefly explained his invention. The famous scientist stated that they were researching a topic they were curious about about DNA repair. Sancar has won the Nobel Prize Human Nucleotide Excision Recovery SystemIt cuts and repairs damaged 26 nucleotide sections of DNA. Sancar also proved this in the test tube; but they wondered if this is the case in the human cell, he said.

Cells almost entered the repair cycle

The scientist stated that they were investigating whether more than 26 nucleotides had been removed or more nucleotides had been added, using a molecule called EdU. Sancar said the results that came out at the time shocked them, saying it was like finding the molecule in intact DNA. pretend they are damaged and activates the repair mechanism.

To expand further, the molecule was placed in the vicinity of intact cells. Afterwards it turned out that the cell activates the repair mechanism and switches off the molecule. When the extracted molecule was released, it re-entered the genome and the same thing happened again. Claiming this cycle continues, Sancar finally Cell that EdU . can’t handle declared he was dead. The scientist emphasizes that in this way it is understood exactly how the molecule kills the cell, and that it can be used for cancer cells.

“EdU molecule can kill tumor without damaging neurons”

Let’s talk about brain cancer. According to the statements, the EdU molecule can easily enter the brain by crossing barriers, unlike chemotherapy drugs. Sancar also states that EdU can be used against cancer because of its cell-killing properties:EdU When given to a patient with brain cancer, it goes to the brain, It enters the DNA of cancer cells and kills the tumor without damaging the neurons. We came to the conclusion.”

The Nobel Prize-winning scientist now says they will team up with a leading brain tumor expert and conduct experiments. We’ll see later if the exciting discovery will solve the brain cancer that affects millions of people.