A new clinical trial CRISPR gene editing technology revealed that it is possible for immune cells to recognize cancer-causing proteins. This is how personalized and effective treatments are realized in the fight against cancer.

In recent years, two areas of cancer research have focused on. CRISPR and immune cell regulation combined with this study. New method in the grip of cancer more than 16 people tried.

Special powers of immune cells in cancer treatment

for the treatment of cancer a magic pill will never be found, because everyone’s cancer is treated as a separate case. Everyone’s genetic makeup is different, and genetic mutations cause cancer. As a result, a different protein must be attacked each time.

That is exactly what the new research focuses on. From the patient himself T cellsIt is being redesigned to recognize and eliminate mutation-causing proteins. This army of T cells is then released to the rest of the body. To achieve this, the researchers took a blood sample from patients and a biopsy from a piece of tumor. Subsequently, proteins found in tumor tissues and those not found in blood were separated. Subsequently, the T cells also produce these proteins. will detect and destroy way adjusted. Modified T cells were transplanted into the patients.

While the disease stabilized in 5 of the 16 participants, only on 2 side effects were seen. It was noted that a limited amount of T cells were used for the experiment, although the effects of the treatment were generally limited. Specialized cells were observed to concentrate on cancerous structures. This confirms the researchers’ theories.

Normally modified T cells facing serious problems with solid tumors. The new research has discovered how these cells can deal with tumors and how they can be more effective. Paper describing the method developed by Joseph Fraietta and his team at the University of Pennsylvania in nature published.